Kate Karelina

B.A. in Psychology, Miami University
M.A. in Psychology, University of Richmond

Thesis Advisor:  A. Courtney DeVries

E-Mail:  karelina.1@osu.edu

Research:

As a member of Dr. A. Courtney DeVries’ lab, I study the effects of social interaction on neuroinflammation following ischemic brain injury. Experimentally induced stroke is followed by a widespread inflammatory response characterized by activation of microglia, and an upregulation of pro- and anti-inflammatory cytokines. My research focus is to determine how the pathophysiological response to stroke differs between socially isolated and paired mice.

Awards:

• 2008-2010   American Heart Association Predoctoral Fellowship
• 2009           Distinguished Lecturer Travel Award, NGSP
• 2008           Alumni Grant for Graduate Research and Scholarship, OSU 
• 2008           Critical Difference for Women Award, OSU

Publications:

Karelina, K, Norman, G, Zhang, N, Morris, J, Peng, H, DeVries, AC (2009) Social Isolation Alters Neuroinflammatory Response to Stroke. Proceedings of the National Academy of Sciences, 106(14):5895-5900.

Karelina, K & Norman, G (2009) Oxytocin influence on the nucleus of the solitary tract: beyond homeostatic regulation. Journal of Neuroscience, 29: 4687-4689.

Broussard, J, Karelina, K, Sarter, M & Givens, B (2009) Cholinergic optimization of cue-evoked parietal activity during challenged attentional performance. European Journal of Neuroscience, 29:1711-1722.

Marchalant, Y, Brothers, HM, Norman, GJ, Karelina, K, DeVries, AC & Wenk, GL (2009) Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. Neurobiology of Disease, 34(2):300-307.

Kinsley, CH., Bardi, M., Karelina, K., Rima, B., Christon, L., Friedenberg, J. & Griffin, G. (2008) Motherhood induces and maintains behavioral and neural plasticity across the lifespan in the rat. Archives of Human Sexual Behavior, 37(1):43-56.

Presentations at Scientific Meetings:

“Oxytocin and ovarian hormones mediate social behavior in Peromyscus leucopus.” Karelina, K, Walton, JC, Weil, ZM, Norman, GJ, Wells, JS, DeVries, AC. Poster for Society of Behavioral Neuroscience meeting, East Lansing, MI, June, 2009.

“Psychosocial Stress Influences Cerebral Ischemia Outcome.” Karelina, K, Norman, GJ, Zhang, N, Morris, JS, Peng, H & DeVries, AC. Poster for A Brain Research Meeting: Stress, Coping and Disease, Arlington, VA., November, 2008.

"Social isolation increases reactive gliosis and stroke damage". Kate Karelina, MA; Greg J. Norman, BS; Ning Zhang, MD; John S. Morris, BS; Haiyan Peng, MS & A. Courtney DeVries, PhD. Poster presented at IBMR, 2008.

“Psychosocial Influences on Neuropathic Pain: Modulation of Mechanical Allodynia and Depressive-like Behavior.” Norman, GJ, Morris, JS, Zhang, N, Karelina, K, Walton, JC & DeVries, AC. Poster for a Brain Research Meeting: Stress, Coping and Disease, Arlington, VA., November, 2008.

“Social Isolation Increases Reactive Gliosis and Stroke Damage.” Karelina, K, Norman, GJ, Zhang, N, Morris, JS, Peng, H & DeVries, AC. Poster for Society for Neuroscience meeting, Washington, D.C., November, 2008.

“Cholinergic regulation of inflammation following global ischemia.” Norman, GJ, Berntson, GG, Weil, ZM, Zhang, N, Karelina, K, Morris JS, Al-Abed, Y, Pavlov, VA, Tracey, KJ & DeVries, AC. Poster for Society for Neuroscience meeting, Washington, D.C., November, 2008.

“Endocannabinoid receptor effects on neuroinflammation and memory in aged rats.” Y. Marchalant, H.M. Brothers, G.J. Norman, K. Karelina, F. Cerbai, A.C. DeVries, G. Wenk. Poster presented at the Society for Neuroscience meeting in San Deigo, CA, 2007.

“Seasonal influences on neuroinflammation and neuronal death.” Karelina, K., Weil, Z., Trainor, B., Zhang, N., DeVries, A.C., & Nelson, R. To be presented at the Society for Neuroscience meeting in San Diego, CA, 2007.