Daniel McKim

Co-Advisors: Jonathan Godbout and John Sheridan
Alumni

 

Research:
 
My research generally concerns how the immune system contributes to physiological and behavioral changes that occur after psychological stress. More specifically, my research concerns the role of interleukin-1 signaling and peripheral monocytes in the development of anxiety-like behavior, impaired learning & memory, and reduced neurogenesis in a mouse model of repeated psychological stress. 
 
Awards:
 

2015 - Oral Presentation Award, Life Sciences Interdisciplinary Graduate Programs Symposium
2015 - Research Day Award, College of Dentistry
2015 - Trave Award, OSUMC Trainee Research Day
2015 - Travel Award, PNIRS
2015 - Hayes Graduate Researc Forum Award, The Ohio State University
2014 - CTOC T32 Fellow, NIH-NIDCR
2014 - Finalist, Edward Hayes Graduate Forum, The Ohio State University
2014 - Travel Award, PNIRS
2012 - OSU University Fellowship, The Ohio State University Graduate School

Publications:

McKim DB, Patterson JM, Wohleb ES, Jarrett BL, Reader BF, Godbout JP, Sheridan JF. (2015) Sympathetic Release of Splenic Monocytes Promotes Recurring Anxiety Following Repeated Social Defeat. Biol Psychiatry. pii: S0006-3223(15)00598-3.

Ramirez K, Shea DT, McKim DB, Reader BF, Sheridan JF. (2015) Imipramine attenuates neuroinflammatory signaling and reverses stress-induced social avoidance. Brain Behav Immun. 46:212-20.

Liu X, Yamashita T, Chen Q, Belevych N, Mckim DB, Tarr AJ, Coppola V, Nath N, Nemeth DP, Syed ZW, Sheridan JF, Godbout JP, Zuo J, Quan N. (2015) Interleukin 1 type 1 receptor restore: a genetic mouse model for studying interleukin 1 receptor-mediated effects in specific cell types. J Neurosci. 35(7):2860-70.

Wohleb ES, McKim DB, Sheridan JF, Godbout JP. (2015) Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior. Front Neurosci. 8:447.

Wohleb ES, McKim DB, Shea DT, Powell ND, Tarr AJ, Sheridan JF, Godbout JP. (2014) Re-establishment of anxiety in stress-sensitized mice is caused by monocyte trafficking from the spleen to the brain. Biol Psychiatry. 75(12):970-81.

Lieblein-Boff JC, McKim DB, Shea DT, Wei P, Deng Z, Sawicki C, Quan N, Bilbo SD, Bailey MT, McTigue DM, Godbout JP. (2013) Neonatal E. coli infection causes neuro-behavioral deficits associated with hypomyelination and neuronal sequestration of iron. J Neurosci. 33(41):16334-45. 

Areas of Expertise
  • Stress and Neuroimmunology
  • Neurotrauma, Neurological Disorders, and Gene Therapy
Education
  • BA in Psychology, William Patterson College
 

Picture for mckim.15

Phone:
(614) 366-3496
247 IBMR
460 Medical Center Drive
Columbus, Ohio 43210