Damon DiSabato

Co-Advisors: Jonathan Godbout and Ning Quan
Graduate Student

 

Research:

My research interests focus on IL-1 signaling and its effects on the various cells of the CNS, particularly in regard to stress and anxiety. I use a myriad of cell-type specific Cre recombinase mouse lines to restrict the expression of IL-1R1 to discrete cells in order to delineate their responses to a murine social defeat paradigm.

Awards:

2017 - College of Dentistry Research Day, Dean's Award for Excellence in Research, 2nd Place

2016 - Fellow, T32 Training Grant NIH-CTOC

2014 - University Fellowship, The Ohio State University Graduate School

Publications:

DiSabato DJ, Quan N, Godbout JP (2016), Neuroinflammation: the devil is in the details. Journal of Neurochemistry. doi: 10.1111/jnc.13607

Liu X, Nemeth DP, Tarr AJ, Belevych N, Syed ZW, Wang Y, Ismail AS, Reed NS, Sheridan JF, Yajnik AR, DiSabato DJ, Zhu L, Quan N (2016), Euflammation attenuates peripheral inflammation-induced neuroinflammation and mitigates immune-to-brain signaling. Brain Behavior and Immunity. doi: 10.1016/j.bbi.2016.01.018

Presentations:

DiSabato, Damon; Nemeth, Danny; Liu Xiaoyu; Gorantla, Gowthami; Godbout, Jonathan; Quan Ning (November 2017). Paired fighting causes social withdrawal and leukocyte recruitment to the cerebral ventricle in an IL-1R1-dependent manner. To be presented 2017 Society for Neuroscience Conference (Washington, DC).
 
DiSabato, Damon; Nemeth, Danny; Liu Xiaoyu; Godbout, Jonathan; Quan Ning (February 2017). Social stress and the induction of neuronal IL-1 expression in the hippocampus activate microglia and cause the recruitment of leukocytes to the brain and spleen. 2017 College of Dentistry Research Day (Columbus, OH).
 

DiSabato, Damon; Nemeth, Danny; Liu, Xiaoyu; Godbout, Jonathan; Quan, Ning (November 2016). Social stress and the induction of neuronal IL-1 expression in the hippocampus activate microglia and cause the recruitment of leukocytes to the brain and spleen. Interactions Between Stress and Immune Function Nanosymposium - 2016 Society for Neuroscience International Meeting (San Diego, CA).

DiSabato, Damon; Liu Xiaoyu; Nemeth, Danny; Godbout, Jonathan; Quan Ning (April 2016). IL-1R1r/r and Paired Fighting: A new paradigm for social stress and anxiety. 2016 Ohio State University IBMR Research Day (Columbus, OH).

DiSabato, Damon; Liu Xiaoyu; Nemeth, Danny; Godbout, Jonathan; Quan Ning (April 2016). IL-1R1r/r and Paired Fighting: A new paradigm for social stress and anxiety. 2016 Ohio State University Wexner Medical Center Research Day (Columbus, OH).

Areas of Expertise
  • Stress and Neuroimmunology
  • Neurotrauma, Neurological Disorders, and Gene Therapy
Education
  • BS in Neuroscience, The Ohio State University
 

Picture for disabato.25

Phone:
614-366-3496
247 IBMR
460 Medical Center Drive
Columbus, OH 43210