My research interests focus on the age-associated dysregulation between the immune system and the central nervous system. I am particularly interested in the impaired signaling between microglia and astrocytes in the aged brain.
2021 - Honorable Mention Health Sciences Oral Presentation, The Ohio State University Edward F. Hayes Graduate Research Forum
2020 - Excellence in Undergraduate Research Mentoring Award, The Ohio State University
2016 - Dean's Distinguished University Fellowship, The Ohio State University Graduate School (3-year award)
Witcher KG, Bray CE, Chunchai T, Zhao F, O’Neil SM, Gordillo A, Campbell WA, McKim DB, Liu X, Dziabis JE, Quan N, Eiferman DS, Fischer A, Kokiko-Cochran ON, Askwith C, Godbout JG. (2021) Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia. J Neurosci. https://www.doi.org/10.1523/JNEUROSCI.2469-20.2020
Kumar JE, Tapp ZM, Witcher KG, Atluri RR, Velasquez J, O’Neil SM., Dziabis J, Bray C, Sheridan JF, Godbout JP, Kokiko-Cochran ON. (2020) Sleep disruption exacerbates and prolongs the inflammatory response to traumatic brain injury. J Neurotrauma. https://www.doi.org/10.1089/neu.2020.7010
DiSabato DJ, Nemeth DP, Liu X, Witcher KG, O'Neil SM, Oliver B, Bray CE, Sheridan JF, Godbout JP, Quan N. (2020) Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress. Mol Psychiatry. https://www.doi.org/10.1038/s41380-020-0788-3
O'Neil SM, Witcher KG, McKim DB, Godbout JP (2018) Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge. Acta Neuropathol Commun. 2018 Nov 26;6(1):129. doi: 10.1186/s40478-018-0636-8.