Lysosomes are acidic organelles full of hydrolases, primarily responsible for the clearance of cellular cargo. However, these multifaceted organelles extend beyond their degradative functions and hold pivotal roles within various cellular processes, particularly during the stress response. Notably, lysosomal dysfunction is a hallmark feature of numerous neurodegenerative diseases.

In the Bonet-Ponce lab, our mission is to unravel the intricacies of lysosomal biology and dynamics, in order to identify potential therapeutic targets aimed at addressing neurodegenerative disorders.